refactor(core): remove global state and implement OptimizationContext

Refactor the optimization pipeline to eliminate module-level global variables,
improving thread safety and modularity. Introduced `OptimizationContext`
to explicitly manage shared state during cylinder evaluation.

Key changes:
- core: Replace global variables with `OptimizationContext` dataclass in
  `objective.py`.
- core: Implement `refine_lateral_longer` in `optimizer.py` for deterministic
  local refinement of screw placement.
- core: Update scoring logic in `scoring.py` to use higher penalties for
  out-of-bone voxels.
- imaging: Add advanced symmetry detection including `best_symmetry_plane`
  and `best_symmetry_axis_angle` in `orientation.py`.
- visualization: Enhance 3D plotting in `res_plot_3d.py` with volume
  absorption rendering (Beer-Lambert law) for an X-ray-like appearance.
- xfr_debug: Implement a custom `_Tee` logger to support multi-process
  logging with volume and level-specific tags.
- chore: Update `.gitignore` to include local logs and kilo directories.
This commit is contained in:
xfr 2026-08-30 00:54:55 +08:00
parent 0274e954be
commit 4f5be3d3e9
13 changed files with 1278 additions and 345 deletions

2
.gitignore vendored
View file

@ -215,4 +215,6 @@ __marimo__/
# Streamlit
.streamlit/secrets.toml
.kilo/
logs/
progress.json

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@ -1,3 +1,6 @@
from dataclasses import dataclass
from typing import Optional
import random
from scipy.ndimage import map_coordinates
@ -9,50 +12,58 @@ from core.cylinder import generate_cylinder_n_torch, generate_cylinder_o_torch,
from core.intersection import center_line_intersections_torch
from core.scoring import cl_score_torch, cl_score_torch_xfr
# Global variables (used in objective_function)
image1_array = None # cortical_nii.gz
image2_array = None # binarynii.gz
image2_shape = None
image3_array = None # roi2.nii.gz
diameter = None
length = None
spacing = [0.5, 0.5, 0.5]
device = None
grid = None
USE_TIP_PENALTY = None
def set_global_context(
cortical,
spine,
shape,
spacing_,
device_,
grid_,
use_tip_penalty=False # 新增
):
global cortical_tensor, spine_tensor, image2_shape, spacing, device, grid, USE_TIP_PENALTY
# =====================================================================
# OptimizationContext: the single explicit container for all shared state
# needed to evaluate a candidate cylinder. New code should build one of
# these and bind it to an objective via make_objective_function[_xfr];
# no module globals are read during optimization.
# =====================================================================
@dataclass
class OptimizationContext:
"""Shared state for evaluating candidate cylinder placements.
Required:
cortical_tensor: cortical bone mask (uint8, 0/1)
spine_tensor: bone (binary) mask (uint8, 0/1)
image2_shape: (Z, Y, X) volume shape
spacing: voxel spacing, [sx, sy, sz] (mm)
device: torch device for tensor ops
Optional:
grid: precomputed coordinate grid (z_t, y_t, x_t)
use_tip_penalty: add the tip-cylinder penalty to the loss
The *_array / spine_roi_tensor / diameter / length fields are kept
for compatibility and debugging; the loss itself does not use them.
"""
cortical_tensor: torch.Tensor
spine_tensor: torch.Tensor
image2_shape: tuple
spacing: list
device: torch.device
grid: Optional[tuple] = None
use_tip_penalty: bool = False
spine_roi_tensor: Optional[torch.Tensor] = None
image1_array: Optional[np.ndarray] = None
image2_array: Optional[np.ndarray] = None
image3_array: Optional[np.ndarray] = None
diameter: Optional[float] = None
length: Optional[float] = None
cortical_tensor = cortical
spine_tensor = spine
image2_shape = shape
spacing = spacing_
device = device_
grid = grid_
USE_TIP_PENALTY = use_tip_penalty
def cylinder_circle_line_intersection_loss_deductions_torch(
ctx: OptimizationContext,
diameter: float,
length: float,
params: list[float],
image_shape: tuple[int, int, int],
cortical_tensor: torch.Tensor,
spine_tensor: torch.Tensor,
spacing: list[float],
device: torch.device
) -> float:
"""
Computes the loss for a given set of cylinder params in PyTorch,
returning a Python float for PSO consumption.
All shared state (tensors, shape, spacing, device, grid, tip penalty)
is taken from `ctx`; no module globals are involved.
"""
position_z, position_y, position_x, azimuth, altitude = params
@ -64,10 +75,10 @@ def cylinder_circle_line_intersection_loss_deductions_torch(
position_x,
float(azimuth),
float(altitude),
image_shape,
spacing,
device,
grid
ctx.image2_shape,
ctx.spacing,
ctx.device,
ctx.grid
)
cyl_opp = generate_cylinder_o_torch(
@ -78,13 +89,12 @@ def cylinder_circle_line_intersection_loss_deductions_torch(
position_x,
float(azimuth),
float(altitude),
image_shape,
spacing,
device,
grid
ctx.image2_shape,
ctx.spacing,
ctx.device,
ctx.grid
)
# We call the center_line_intersections in Torch mode
intersections, _ = center_line_intersections_torch(
position_z,
@ -93,73 +103,37 @@ def cylinder_circle_line_intersection_loss_deductions_torch(
azimuth,
altitude,
length,
spine_tensor,
spacing,
device
ctx.spine_tensor,
ctx.spacing,
ctx.device
)
cyl_tip = None
if USE_TIP_PENALTY:
if ctx.use_tip_penalty:
cyl_tip = generate_cylinder_tip_torch(
diameter, length,
position_z, position_y, position_x,
float(azimuth), float(altitude),
image_shape, spacing, device, grid
ctx.image2_shape, ctx.spacing, ctx.device, ctx.grid
)
# loss_value = cl_score_torch(
loss_value = cl_score_torch_xfr(
cortical_tensor, spine_tensor,
ctx.cortical_tensor, ctx.spine_tensor,
cyl_fwd, cyl_opp, intersections,
cylinder_tip_torch=cyl_tip
)
return loss_value
def objective_function_xfr(params: list[float], y_indices) -> float:
# =====================================================================
# Context-bound objective builders (preferred API)
# =====================================================================
def _evaluate(params: list[float], ctx: OptimizationContext) -> float:
"""
Wrapper for the PSO objective function, calling our Torch-based loss function.
Now params includes diameter and length at the end.
params = [position_z, position_y, position_x, azimuth, altitude, diameter_raw, length_raw]
"""
# position_params = params[:5] # [z, y, x, azimuth, altitude]
# diameter_raw = params[5]
# length_raw = params[6]
z, x, azimuth, altitude, diameter_raw, length_raw = params
y = y_indices[round(z), round(x)] #+ random.uniform(-0.5, 0.5)
# coords = np.array([[z], [x]])
# result = map_coordinates(y_indices, coords, order=1)
# y= result[0]
position_params = [z, y, x, azimuth, altitude]
# 將連續值轉換為離散值
# diameter_discrete, length_discrete = snap_to_discrete_values(diameter_raw, length_raw)
diameter_discrete, length_discrete = snap_to_discrete_values_xfr(diameter_raw, length_raw)
diameter_loss = .9*diameter_discrete + .1*diameter_raw
length_loss = .9* length_discrete + .1* length_raw
loss = cylinder_circle_line_intersection_loss_deductions_torch(
diameter_loss,
length_loss,
position_params,
image2_shape,
cortical_tensor,
spine_tensor,
spacing,
device
)
return loss
def objective_function(params: list[float]) -> float:
"""
Wrapper for the PSO objective function, calling our Torch-based loss function.
Now params includes diameter and length at the end.
params = [position_z, position_y, position_x, azimuth, altitude, diameter_raw, length_raw]
Core objective: params = [z, y, x, azimuth, altitude, diameter_raw, length_raw]
"""
position_params = params[:5] # [z, y, x, azimuth, altitude]
diameter_raw = params[5]
@ -168,14 +142,161 @@ def objective_function(params: list[float]) -> float:
# 將連續值轉換為離散值
diameter_discrete, length_discrete = snap_to_discrete_values(diameter_raw, length_raw)
loss = cylinder_circle_line_intersection_loss_deductions_torch(
return cylinder_circle_line_intersection_loss_deductions_torch(
ctx,
diameter_discrete,
length_discrete,
position_params,
image2_shape,
cortical_tensor,
spine_tensor,
spacing,
device
position_params
)
return loss
def _evaluate_xfr(params: list[float], ctx: OptimizationContext, y_indices) -> float:
"""
Core xfr objective: params = [z, x, azimuth, altitude, diameter_raw, length_raw];
y is derived from the per-column `y_indices` surface.
"""
z, x, azimuth, altitude, diameter_raw, length_raw = params
y = y_indices[round(z), round(x)] #+ random.uniform(-0.5, 0.5)
position_params = [z, y, x, azimuth, altitude]
# 將連續值轉換為離散值
diameter_discrete, length_discrete = snap_to_discrete_values_xfr(diameter_raw, length_raw)
diameter_loss = .9*diameter_discrete + .1*diameter_raw
length_loss = .9* length_discrete + .1* length_raw
return cylinder_circle_line_intersection_loss_deductions_torch(
ctx,
diameter_loss,
length_loss,
position_params
)
def make_objective_function(ctx: OptimizationContext):
"""
Return an objective function bound to `ctx`.
Pass the returned callable directly to pso / differential_evolution / minimize.
"""
def objective(params: list[float]) -> float:
return _evaluate(params, ctx)
return objective
def make_objective_function_xfr(ctx: OptimizationContext, y_indices):
"""
Return an xfr objective function bound to `ctx` and the `y_indices` surface.
Pass the returned callable directly to pso / differential_evolution / minimize.
"""
def objective(params: list[float]) -> float:
return _evaluate_xfr(params, ctx, y_indices)
return objective
# =====================================================================
# Legacy API (backward compatible)
#
# The old flow mutated module attributes on this file from the optimizers
# ("跨檔案注入變數"), which was fragile: any forgotten attribute showed up
# deep inside an optimizer callback as a NoneType/NameError. It is kept so
# existing callers (set_global_context + objective_function) keep working,
# but new code should use OptimizationContext + the make_* factories.
# =====================================================================
# Module-level state for the legacy path only.
cortical_tensor = None
spine_tensor = None
image1_array = None # cortical_nii.gz
image2_array = None # binarynii.gz
image2_shape = None
image3_array = None # roi2.nii.gz
diameter = None
length = None
spacing = [0.5, 0.5, 0.5]
device = None
grid = None
USE_TIP_PENALTY = None
_current_context: Optional[OptimizationContext] = None
def set_global_context(
cortical,
spine,
shape,
spacing_,
device_,
grid_,
use_tip_penalty=False
):
"""
Legacy: set the process-wide context used by the legacy
objective_function / objective_function_xfr wrappers.
Returns the built OptimizationContext for convenience.
"""
global _current_context
global cortical_tensor, spine_tensor, image2_shape, spacing, device, grid, USE_TIP_PENALTY
_current_context = OptimizationContext(
cortical_tensor=cortical,
spine_tensor=spine,
image2_shape=shape,
spacing=spacing_,
device=device_,
grid=grid_,
use_tip_penalty=use_tip_penalty,
)
# mirror into legacy module attributes for any code that reads them
cortical_tensor = cortical
spine_tensor = spine
image2_shape = shape
spacing = spacing_
device = device_
grid = grid_
USE_TIP_PENALTY = use_tip_penalty
return _current_context
def _active_context() -> OptimizationContext:
"""Resolve the context for the legacy wrappers, with a clear error."""
if _current_context is not None:
return _current_context
# Fallback: a caller (old-style optimizers) may have set the legacy
# module attributes directly — rebuild a context from them.
if cortical_tensor is not None and spine_tensor is not None:
return OptimizationContext(
cortical_tensor=cortical_tensor,
spine_tensor=spine_tensor,
image2_shape=image2_shape,
spacing=spacing,
device=device,
grid=grid,
use_tip_penalty=bool(USE_TIP_PENALTY),
)
raise RuntimeError(
"No optimization context available. Either call set_global_context(...) "
"or (preferred) build an OptimizationContext and use "
"make_objective_function / make_objective_function_xfr."
)
def objective_function(params: list[float]) -> float:
"""
Legacy wrapper: evaluates against the context set by set_global_context.
params = [z, y, x, azimuth, altitude, diameter_raw, length_raw]
"""
return _evaluate(params, _active_context())
def objective_function_xfr(params: list[float], y_indices) -> float:
"""
Legacy wrapper: evaluates against the context set by set_global_context.
params = [z, x, azimuth, altitude, diameter_raw, length_raw]
"""
return _evaluate_xfr(params, _active_context(), y_indices)

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@ -2,16 +2,89 @@ import time
from datetime import datetime
import SimpleITK as sitk
import torch
from imaging.orientation import azimuth_rotation, analyze_vertebral_tilt_contour
from imaging.orientation import (azimuth_rotation, analyze_vertebral_tilt_contour,
best_symmetry_plane, best_upper_endplate_plane,
segment_spinous_process)
from config.constant import ALLOWED_DIAMETERS, ALLOWED_LENGTHS
from core.objective import objective_function, objective_function_xfr
from core.objective import OptimizationContext, make_objective_function, make_objective_function_xfr
from pyswarm import pso
import core.objective # <--- 加入這行,讓我們可以直接操作 objective 模組
from core.cylinder import generate_cylinder_n_torch, snap_to_discrete_values, create_coordinate_grid, snap_to_discrete_values_xfr
from core.scoring import compute_overlap_ratio_from_cylinder_mask, is_solution_ok
from core.cylinder import generate_cylinder_n_torch, generate_cylinder_o_torch, snap_to_discrete_values, create_coordinate_grid, snap_to_discrete_values_xfr
from core.intersection import center_line_intersections_torch
from core.scoring import compute_overlap_ratio_from_cylinder_mask, is_solution_ok, cl_score_torch_xfr
from config.constant import OVERLAP_THRESH
from visualization.res_plot_3d import res_plt_2_torch
LATERAL_REFINE_MIN_IN_BONE = 0.97
def refine_lateral_longer(
z, x, azimuth, altitude, diameter_raw, length_raw,
side, az_bounds, x_bounds, y_indices,
image_shape, spacing, device, grid,
cortical_tensor, spine_tensor,
):
"""
Deterministic local refinement after PSO: try aiming more laterally and
using a longer screw. Only accepts a candidate if it stays
>= LATERAL_REFINE_MIN_IN_BONE inside bone AND improves the score.
left (x-lower half): more lateral = larger azimuth, entry shifted toward -x
right (x-upper half): more lateral = smaller azimuth, entry shifted toward +x
"""
def _score_candidate(cand):
z_c, x_c, az_c, alt_c, d_c, L_c = cand
y_c = y_indices[round(z_c), round(x_c)]
if y_c < 0:
return None
cyl = generate_cylinder_n_torch(d_c, L_c, z_c, y_c, x_c, az_c, alt_c,
image_shape, spacing, device, grid)
cyl_o = generate_cylinder_o_torch(d_c, L_c, z_c, y_c, x_c, az_c, alt_c,
image_shape, spacing, device, grid)
if cyl.sum().item() == 0:
return None
inter, _ = center_line_intersections_torch(z_c, y_c, x_c, az_c, alt_c,
L_c, spine_tensor, spacing, device)
loss = cl_score_torch_xfr(cortical_tensor, spine_tensor, cyl, cyl_o, inter)
in_bone = ((spine_tensor == 1) & (cyl == 1)).sum().item() / cyl.sum().item()
return {'pos': cand, 'loss': loss, 'in_bone': in_bone}
d_snap, L_snap = snap_to_discrete_values_xfr(diameter_raw, length_raw)
az_lo, az_hi = az_bounds
x_lo, x_hi = x_bounds
az_steps = [0.0, 5.0, 10.0, 15.0] if side == "L" else [0.0, -5.0, -10.0, -15.0]
x_shifts = [0.0, -4.0, -8.0] if side == "L" else [0.0, 4.0, 8.0]
best = _score_candidate((z, x, azimuth, altitude, d_snap, L_snap))
if best is None:
return z, x, azimuth, altitude, diameter_raw, length_raw, False, None
for ds in az_steps:
az_c = min(az_hi - 0.01, max(az_lo + 0.01, azimuth + ds))
if abs(az_c - azimuth) < 0.5 and ds != 0:
continue
for dx in x_shifts:
x_c = min(x_hi, max(x_lo, x + dx))
if abs(x_c - x) < 0.5 and dx != 0:
continue
for L_c in sorted({L_snap} | {l for l in ALLOWED_LENGTHS if l > L_snap}):
cand = _score_candidate((z, x_c, az_c, altitude, d_snap, L_c))
if cand is None:
continue
if cand['in_bone'] >= LATERAL_REFINE_MIN_IN_BONE and cand['loss'] < best['loss']:
best = cand
z_r, x_r, az_r, alt_r, d_r, L_r = best['pos']
adopted = not (abs(z_r - z) < 1e-6 and abs(x_r - x) < 1e-6
and abs(az_r - azimuth) < 1e-6 and abs(L_r - L_snap) < 1e-6)
return z_r, x_r, az_r, alt_r, d_r, L_r, adopted, best
def _validate_bounds(lb, ub, name):
for i, (lo, hi) in enumerate(zip(lb, ub)):
if lo >= hi:
raise ValueError(f'PSO bounds invalid for {name}: dim {i} lower {lo} >= upper {hi}')
def get_first_nonzero_y(arr):
OUTSIDE_VALUE = -100
@ -80,59 +153,100 @@ def run_pso_torch_xfr(
spine_tensor = torch.from_numpy(image2_array).to(device=device, dtype=torch.uint8)
spine_roi_tensor = torch.from_numpy(image3_array).to(device=device, dtype=torch.uint8)
# ================= [跨檔案注入變數:終極防呆版] =================
import core.objective
# 1. 注入 Tensors
core.objective.cortical_tensor = cortical_tensor
core.objective.spine_tensor = spine_tensor
core.objective.spine_roi_tensor = spine_roi_tensor
# 2. 注入 Arrays (以防 objective 裡面偷偷用到 Numpy 陣列)
core.objective.image1_array = image1_array
core.objective.image2_array = image2_array
core.objective.image3_array = image3_array
# 3. 注入 Shapes (這就是導致這次 NoneType 報錯的真兇!)
core.objective.image2_shape = image2_shape # <--- 解除警報的最關鍵一行
core.objective.image_shape = image_shape
core.objective.shape = image_shape
# 4. 注入環境變數
core.objective.spacing = spacing
core.objective.device = device
core.objective.grid = grid
# 5. 注入尺寸參數 (兼容固定尺寸模式)
if not optimize_size:
core.objective.diameter = diameter
core.objective.length = length
# ==============================================================
# 建立明確的優化上下文(取代舊的跨檔案 global 注入;狀態全部顯式傳入目標函數)
ctx = OptimizationContext(
cortical_tensor=cortical_tensor,
spine_tensor=spine_tensor,
spine_roi_tensor=spine_roi_tensor,
image1_array=image1_array,
image2_array=image2_array,
image3_array=image3_array,
image2_shape=image2_shape,
spacing=spacing,
device=device,
grid=grid,
diameter=diameter if not optimize_size else None,
length=length if not optimize_size else None,
)
azi = azimuth_rotation(image2_path)
res = analyze_vertebral_tilt_contour(image2_path, edge_type='superior', show_plot=False, debug=False)
alt = res['superior']['tilt_angle_deg']
# ===== az/alt 搜尋範圍錨點:以椎體自身座標系取代 2D 近似 =====
# 鏡稱對稱面(最佳 mirror plane法線 (s_nx, s_ny, s_nz)s_nx>0 固定符號
# theta_v = atan2(s_ny, s_nx) 是椎體真實左右軸相對 +x 的旋轉角,
# 取代舊 2D 輪廓前點角 azi舊式 az 中心 90-azi == 新式 90+theta_v
# 上終板面normal 朝上, e_nz>0
# tau_y = atan2(e_ny, e_nz):終板 AP 面傾斜;負 = 面向 +y終板側升高
# 軌跡需爬得更陡 → altitude 中心減小(舊式 65-alt 的 3D 版)。
# tau_x = atan2(e_nx, e_nz):終板 LR 面傾斜;正 = 面向小 xL 側)升高,
# L 側需更陡(-tau_x、R 側較平(+tau_x
sym_plane = best_symmetry_plane(image2_array)
# 入口面 y_indices 取「每個 (z,x) 柱第一個 bone voxel最後側
# 中線柱會落在棘突上(入口太靠內後)。先把棘突(鏡稱面中線後側,
# 見 segment_spinous_process從 image2_array 移除再取 surface
# 讓 y_indices 永不落在棘突上loss 用 spine_tensor不受影響
sp_mask, sp_th, sp_info = segment_spinous_process(image2_array, sym_plane)
if sp_mask is not None and sp_mask.any():
n_sp = int(sp_mask.sum())
image2_array[sp_mask] = 0
print(f"[Y-INDEX] spinous process removed from entry surface: {n_sp} vox "
f"(band=+/-{sp_info['band_w']:.1f} voxel, AP>={sp_info['ap_thresh']:.1f}, "
f"mode={sp_info['mode']})")
y_indices = get_first_nonzero_y(image2_array)
objective_fn = make_objective_function_xfr(ctx, y_indices)
s_nx, s_ny, s_nz = sym_plane['normal']
theta_v = float(np.degrees(np.arctan2(s_ny, s_nx)))
endplate_plane = best_upper_endplate_plane(image2_array)
if endplate_plane is not None:
e_nx, e_ny, e_nz = endplate_plane['normal']
tau_y = float(np.degrees(np.arctan2(e_ny, e_nz)))
tau_x = float(np.degrees(np.arctan2(e_nx, e_nz)))
else:
tau_y, tau_x = 0.0, 0.0
print(f"[PLANE] mirror : {sym_plane['plane'][0]:+.3f}x {sym_plane['plane'][1]:+.3f}y "
f"{sym_plane['plane'][2]:+.3f}z = {sym_plane['plane'][3]:.1f}"
f" (theta_v={theta_v:+.2f} deg, mirror ratio={sym_plane['ratio']:.3f})")
if endplate_plane is not None:
p = endplate_plane['plane']
print(f"[PLANE] endplate: {p[0]:+.3f}x {p[1]:+.3f}y {p[2]:+.3f}z = {p[3]:.1f}"
f" (tau_y={tau_y:+.2f} deg, tau_x={tau_x:+.2f} deg, "
f"inlier={endplate_plane['inlier_ratio']:.2f})")
else:
print("[PLANE] endplate: 資料不足altitude 錨點退回 tau_y=tau_x=0")
# flat_min_index = np.argmin(y_indices)
# z_border, x_border = np.unravel_index(flat_min_index, y_indices.shape)
x_with_nonzero = np.where(np.any(image2_array[:,image_shape[1]//10,:] != 0, axis=0))[0]
# 脊椎中線:整段 (全體積) 骨頭 x 範圍的中點。
# 不取單一行的原因 (0005 L5):椎體軸狀面旋轉時單行只罩到單側骨塊
# (x 1..76 / W=224 → x_mid≈0.17W)L/R 兩個 band 被壓到同一側。
# 不用鏡稱對稱軸的原因 (0001 L4):逐切面對稱軸會被肋、後側要素
# 左右不對稱與椎體傾斜牽引 (69.0 vs 範圍中點 74.5),把 R band 內緣
# (x_mid+0.1W) 拉進中線棘突/椎板區R 側入口落在棘突上 (太靠內後)。
# Laminectomy 只移除中線後側要素,左右極端 x 位置不變,
# 所以範圍中點同樣不受其影響,作為 L/R band 分割線比對稱軸穩定。
x_with_nonzero = np.where(np.any(image2_array != 0, axis=(0, 1)))[0]
x1 = x_with_nonzero[0]
x2 = x_with_nonzero[-1]
x_width = x2 - x1
# print(x1,x2)
# exit()
x_mid = (x1+x2)/2
x1 = x_mid-image_shape[2]*.1
x2 = x_mid+image_shape[2]*.1
# x_mid = (x1 + x2) / 2
# x1 = x_mid-image_shape[2]*.1
# x2 = x_mid+image_shape[2]*.1
z_sum = np.sum(image2_array, axis=(1, 2))
z_with_nonzero = np.where(z_sum > 0)[0]
z1 = z_with_nonzero[0]
z2 = z_with_nonzero[-1]
z_height = z2-z1
# print(x1,x2)
# exit()
@ -149,18 +263,37 @@ def run_pso_torch_xfr(
if CBT == True:
# z_bounds = (0, image_shape[0]-1)
# z_bounds = (z1, (z1+z2)/2)
z_bounds = (.1*image_shape[0], .8*image_shape[0])
# z_bounds = (.1*image_shape[0], .8*image_shape[0])
z_bounds = (z1+z_height*.1, z1+z_height*.9)
# x_bounds_right = (image_shape[2]/2 + image_shape[2]/10, image_shape[2] - 1)
# x_bounds_left = (0, image_shape[2]/2 - image_shape[2]/10 - 1)
x_bounds_right = (x2, image_shape[2]*.9)
x_bounds_left = (image_shape[2]*.1, x1)
# x_bounds_right = (x2, image_shape[2]*.9)
# x_bounds_left = (image_shape[2]*.1, x1)
x_bounds_right = (x1+x_width*.6, +x_width*.9)
x_bounds_left = (x1+x_width*.1, +x_width*.4)
# azimuth_bounds_l = ((95-azi), (145-azi))
# azimuth_bounds_r = ((50-azi), (85-azi))
# altitude_bounds = ((60-alt), (75-alt))
azimuth_bounds_l = ((98-azi), (120-azi))
azimuth_bounds_r = ((60-azi), (82-azi))
altitude_bounds = ((60-alt), (70-alt))
# 脊椎若被體積邊界切到(真正偏心、骨頭貼著左/右邊緣),
# 對應那側的 x band 下限會 >= 上限PSO 會丟 "upper-bound must be greater"。
# 出錯時 clamp 成同側最小寬度5% 寬度)的合法 band。
min_band = .05 * image_shape[2]
if x_bounds_left[1] <= x_bounds_left[0]:
x_bounds_left = (x_bounds_left[0], x_bounds_left[0] + min_band)
if x_bounds_right[0] >= x_bounds_right[1]:
x_bounds_right = (x_bounds_right[1] - min_band, x_bounds_right[1])
# 舊 2D 版本(以輪廓角 azi / 矢狀面傾斜 alt 平移固定範圍),保留供對照:
# azimuth_bounds_l = ((98-azi), (120-azi))
# azimuth_bounds_r = ((60-azi), (82-azi))
# altitude_bounds = ((60-alt), (70-alt))
# 新:範圍以「椎體自身座標系」為中心 —— 椎體系中 az=90° 是 AP 直向、
# L 帶 = AP 後退 8~30°偏 -x、R 帶 = AP 前進 8~30°偏 +x
# altitude 60~70。再換算回影像系az 整體加 theta_v鏡稱面
# altitude 加 tau_y終板 AP 傾斜)並逐側加 -/+tau_x終板 LR 傾斜)。
azimuth_bounds_l = ((98+theta_v), (120+theta_v))
azimuth_bounds_r = ((60+theta_v), (82+theta_v))
altitude_bounds_l = ((60+tau_y-tau_x), (70+tau_y-tau_x))
altitude_bounds_r = ((60+tau_y+tau_x), (70+tau_y+tau_x))
else:
z_bounds = (0, image_shape[0] - 1)
@ -170,6 +303,9 @@ def run_pso_torch_xfr(
azimuth_bounds_l = (60-azi, 90-azi)
azimuth_bounds_r = (90-azi, 120-azi)
altitude_bounds = (65-alt, 80-alt)
# 非 CBT 分支維持單一式,兩側同用
altitude_bounds_l = altitude_bounds
altitude_bounds_r = altitude_bounds
def eval_overlap_from_position(pos, side: str, optimize_size: bool,
spine_tensor: torch.Tensor,
@ -204,16 +340,16 @@ def run_pso_torch_xfr(
diameter_bounds = (min(ALLOWED_DIAMETERS), max(ALLOWED_DIAMETERS)*1.01)
length_bounds = (min(ALLOWED_LENGTHS), max(ALLOWED_LENGTHS)*1.01)
# bounds 現在有 7 個參數
# bounds 現在有 7 個參數altitude 分 L/R 兩側,由終板面 tau_x 決定)
lb_l = [z_bounds[0], x_bounds_left[0], azimuth_bounds_l[0],
altitude_bounds[0], diameter_bounds[0], length_bounds[0]]
altitude_bounds_l[0], diameter_bounds[0], length_bounds[0]]
ub_l = [z_bounds[1], x_bounds_left[1], azimuth_bounds_l[1],
altitude_bounds[1], diameter_bounds[1], length_bounds[1]]
altitude_bounds_l[1], diameter_bounds[1], length_bounds[1]]
lb_r = [z_bounds[0], x_bounds_right[0], azimuth_bounds_r[0],
altitude_bounds[0], diameter_bounds[0], length_bounds[0]]
altitude_bounds_r[0], diameter_bounds[0], length_bounds[0]]
ub_r = [z_bounds[1], x_bounds_right[1], azimuth_bounds_r[1],
altitude_bounds[1], diameter_bounds[1], length_bounds[1]]
altitude_bounds_r[1], diameter_bounds[1], length_bounds[1]]
else:
# 模式 2固定 diameter 和 length向後兼容
@ -222,11 +358,11 @@ def run_pso_torch_xfr(
diameter = 4.5 # 或從參數傳入
length = 45 # 或從參數傳入
lb_l = [z_bounds[0], y_bounds[0], x_bounds_left[0], azimuth_bounds_l[0], altitude_bounds[0]]
ub_l = [z_bounds[1], y_bounds[1], x_bounds_left[1], azimuth_bounds_l[1], altitude_bounds[1]]
lb_l = [z_bounds[0], y_bounds[0], x_bounds_left[0], azimuth_bounds_l[0], altitude_bounds_l[0]]
ub_l = [z_bounds[1], y_bounds[1], x_bounds_left[1], azimuth_bounds_l[1], altitude_bounds_l[1]]
lb_r = [z_bounds[0], y_bounds[0], x_bounds_right[0], azimuth_bounds_r[0], altitude_bounds[0]]
ub_r = [z_bounds[1], y_bounds[1], x_bounds_right[1], azimuth_bounds_r[1], altitude_bounds[1]]
lb_r = [z_bounds[0], y_bounds[0], x_bounds_right[0], azimuth_bounds_r[0], altitude_bounds_r[0]]
ub_r = [z_bounds[1], y_bounds[1], x_bounds_right[1], azimuth_bounds_r[1], altitude_bounds_r[1]]
if True or debug:
print(lb_l)
@ -241,17 +377,31 @@ def run_pso_torch_xfr(
# Left side optimization
print(f"\n=== {label_str} 左側 ===")
kwargs = {'y_indices': y_indices}
position_l, loss_l = pso(objective_function_xfr, lb_l, ub_l,
_validate_bounds(lb_l, ub_l, f'{label_str} L')
position_l, loss_l = pso(objective_fn, lb_l, ub_l,
# ieqcons=[constraint_y],
kwargs=kwargs,
swarmsize=swarm_size,
omega = omega,
maxiter=max_iter, debug=debug)
z, x, azimuth, altitude, diameter, length = position_l
az_pso, x_pso, L_pso = azimuth, x, length
y = y_indices[round(z), round(x)]
z, x, azimuth, altitude, diameter, length, adopted_l, ref_l = refine_lateral_longer(
z, x, azimuth, altitude, diameter, length,
"L", azimuth_bounds_l, x_bounds_left, y_indices,
image_shape, spacing, device, grid,
cortical_tensor, spine_tensor,
)
y = y_indices[round(z), round(x)]
if adopted_l:
loss_l = ref_l['loss']
print(f"[LEFT] lateral-refine: az {az_pso:.2f} -> {azimuth:.2f}, x {x_pso:.2f} -> {x:.2f}, "
f"L {L_pso:.2f} -> {length:.2f}, in-bone {ref_l['in_bone']*100:.1f}%")
else:
print("[LEFT] lateral-refine: no improvement")
position_l = z, y, x, azimuth, altitude, diameter, length
overlap_l, diameter_l, length_l = eval_overlap_from_position(
@ -277,7 +427,7 @@ def run_pso_torch_xfr(
# 左側 retryloss 要 <=0 且 overlap >= 0.5 才算過關
# while (best_loss_l > 0 or best_overlap_l < OVERLAP_THRESH) and retries < max_retries:
# position_l, loss_l = pso(objective_function, lb_l, ub_l, swarmsize=swarm_size, maxiter=max_iter)
# position_l, loss_l = pso(objective_fn, lb_l, ub_l, swarmsize=swarm_size, maxiter=max_iter)
# overlap_l, diameter_l, length_l = eval_overlap_from_position(
# position_l, "L", optimize_size, spine_tensor, image_shape, spacing
# )
@ -307,15 +457,31 @@ def run_pso_torch_xfr(
# Right side optimization
print(f"\n=== {label_str} 右側 ===")
position_r, loss_r = pso(objective_function_xfr, lb_r, ub_r,
_validate_bounds(lb_r, ub_r, f'{label_str} R')
position_r, loss_r = pso(objective_fn, lb_r, ub_r,
# ieqcons=[constraint_y],
kwargs=kwargs,
swarmsize=swarm_size,
omega = omega,
maxiter=max_iter, debug=debug)
z, x, azimuth, altitude, diameter, length = position_r
az_pso, x_pso, L_pso = azimuth, x, length
y = y_indices[round(z), round(x)]
z, x, azimuth, altitude, diameter, length, adopted_r, ref_r = refine_lateral_longer(
z, x, azimuth, altitude, diameter, length,
"R", azimuth_bounds_r, x_bounds_right, y_indices,
image_shape, spacing, device, grid,
cortical_tensor, spine_tensor,
)
y = y_indices[round(z), round(x)]
if adopted_r:
loss_r = ref_r['loss']
print(f"[RIGHT] lateral-refine: az {az_pso:.2f} -> {azimuth:.2f}, x {x_pso:.2f} -> {x:.2f}, "
f"L {L_pso:.2f} -> {length:.2f}, in-bone {ref_r['in_bone']*100:.1f}%")
else:
print("[RIGHT] lateral-refine: no improvement")
position_r = z, y, x, azimuth, altitude, diameter, length
overlap_r, diameter_r, length_r = eval_overlap_from_position(
@ -345,7 +511,7 @@ def run_pso_torch_xfr(
# retries = 0
# while (best_loss_r > 0 or best_overlap_r < OVERLAP_THRESH) and retries < max_retries:
# position_r, loss_r = pso(objective_function, lb_r, ub_r, swarmsize=swarm_size, maxiter=max_iter)
# position_r, loss_r = pso(objective_fn, lb_r, ub_r, swarmsize=swarm_size, maxiter=max_iter)
# overlap_r, diameter_r, length_r = eval_overlap_from_position(
# position_r, "R", optimize_size, spine_tensor, image_shape, spacing
# )
@ -458,34 +624,22 @@ def run_pso_torch(
spine_tensor = torch.from_numpy(image2_array).to(device=device, dtype=torch.uint8)
spine_roi_tensor = torch.from_numpy(image3_array).to(device=device, dtype=torch.uint8)
# ================= [跨檔案注入變數:終極防呆版] =================
import core.objective
# 1. 注入 Tensors
core.objective.cortical_tensor = cortical_tensor
core.objective.spine_tensor = spine_tensor
core.objective.spine_roi_tensor = spine_roi_tensor
# 2. 注入 Arrays (以防 objective 裡面偷偷用到 Numpy 陣列)
core.objective.image1_array = image1_array
core.objective.image2_array = image2_array
core.objective.image3_array = image3_array
# 3. 注入 Shapes (這就是導致這次 NoneType 報錯的真兇!)
core.objective.image2_shape = image2_shape # <--- 解除警報的最關鍵一行
core.objective.image_shape = image_shape
core.objective.shape = image_shape
# 4. 注入環境變數
core.objective.spacing = spacing
core.objective.device = device
core.objective.grid = grid
# 5. 注入尺寸參數 (兼容固定尺寸模式)
if not optimize_size:
core.objective.diameter = diameter
core.objective.length = length
# ==============================================================
# 建立明確的優化上下文(取代舊的跨檔案 global 注入;狀態全部顯式傳入目標函數)
ctx = OptimizationContext(
cortical_tensor=cortical_tensor,
spine_tensor=spine_tensor,
spine_roi_tensor=spine_roi_tensor,
image1_array=image1_array,
image2_array=image2_array,
image3_array=image3_array,
image2_shape=image2_shape,
spacing=spacing,
device=device,
grid=grid,
diameter=diameter if not optimize_size else None,
length=length if not optimize_size else None,
)
objective_fn = make_objective_function(ctx)
azi = azimuth_rotation(image2_path)
res = analyze_vertebral_tilt_contour(image2_path, edge_type='superior', show_plot=False, debug=False)
@ -497,9 +651,11 @@ def run_pso_torch(
y_bounds = (image_shape[1]/5, image_shape[1]/2 - 1)
x_bounds_right = (image_shape[2]/2 + image_shape[2]/10, image_shape[2] - 1)
x_bounds_left = (0, image_shape[2]/2 - image_shape[2]/10 - 1)
azimuth_bounds_l = ((95-azi), (145-azi))
azimuth_bounds_r = ((50-azi), (85-azi))
altitude_bounds = ((60-alt), (75-alt))
# CBT 參數依據 references/Santoni 2009 (Spine J 9:366) 冠狀面 25-30° cranial (caudo-cephalad)、
# 軸狀面自正中線向外 (medial→lateral) ≤30°Delgado-Fernandez 2017 (ASJ 11:817)、Kim 2022 (SSRR 6:1)
azimuth_bounds_l = ((98-azi), (120-azi))
azimuth_bounds_r = ((60-azi), (82-azi))
altitude_bounds = ((60-alt), (70-alt))
# xfr
# z_bounds = (0, image_shape[0] - 1)
@ -588,7 +744,7 @@ def run_pso_torch(
# Left side optimization
print("\n=== 左側 ===")
position_l, loss_l = pso(objective_function, lb_l, ub_l, swarmsize=swarm_size, maxiter=max_iter, debug=debug)
position_l, loss_l = pso(objective_fn, lb_l, ub_l, swarmsize=swarm_size, maxiter=max_iter, debug=debug)
overlap_l, diameter_l, length_l = eval_overlap_from_position(
position_l, "L", optimize_size, spine_tensor, image_shape, spacing
@ -612,7 +768,7 @@ def run_pso_torch(
# 左側 retryloss 要 <=0 且 overlap >= 0.5 才算過關
# while (best_loss_l > 0 or best_overlap_l < OVERLAP_THRESH) and retries < max_retries:
# position_l, loss_l = pso(objective_function, lb_l, ub_l, swarmsize=swarm_size, maxiter=max_iter)
# position_l, loss_l = pso(objective_fn, lb_l, ub_l, swarmsize=swarm_size, maxiter=max_iter)
# overlap_l, diameter_l, length_l = eval_overlap_from_position(
# position_l, "L", optimize_size, spine_tensor, image_shape, spacing
# )
@ -642,7 +798,7 @@ def run_pso_torch(
# Right side optimization
print("\n=== 右側 ===")
position_r, loss_r = pso(objective_function, lb_r, ub_r, swarmsize=swarm_size, maxiter=max_iter, debug=debug)
position_r, loss_r = pso(objective_fn, lb_r, ub_r, swarmsize=swarm_size, maxiter=max_iter, debug=debug)
overlap_r, diameter_r, length_r = eval_overlap_from_position(
position_r, "R", optimize_size, spine_tensor, image_shape, spacing
)
@ -670,7 +826,7 @@ def run_pso_torch(
# retries = 0
# while (best_loss_r > 0 or best_overlap_r < OVERLAP_THRESH) and retries < max_retries:
# position_r, loss_r = pso(objective_function, lb_r, ub_r, swarmsize=swarm_size, maxiter=max_iter)
# position_r, loss_r = pso(objective_fn, lb_r, ub_r, swarmsize=swarm_size, maxiter=max_iter)
# overlap_r, diameter_r, length_r = eval_overlap_from_position(
# position_r, "R", optimize_size, spine_tensor, image_shape, spacing
# )
@ -748,7 +904,6 @@ from scipy.optimize import differential_evolution
from scipy.optimize import minimize
from imaging.orientation import azimuth_rotation, analyze_vertebral_tilt_contour
from config.constant import ALLOWED_DIAMETERS, ALLOWED_LENGTHS
from core.objective import objective_function
from core.cylinder import generate_cylinder_n_torch, snap_to_discrete_values, create_coordinate_grid
from core.scoring import compute_overlap_ratio_from_cylinder_mask, is_solution_ok
from config.constant import OVERLAP_THRESH
@ -790,34 +945,22 @@ def run_de_torch(
spine_tensor = torch.from_numpy(image2_array).to(device=device, dtype=torch.uint8)
spine_roi_tensor = torch.from_numpy(image3_array).to(device=device, dtype=torch.uint8)
# ================= [跨檔案注入變數:終極防呆版] =================
import core.objective
# 1. 注入 Tensors
core.objective.cortical_tensor = cortical_tensor
core.objective.spine_tensor = spine_tensor
core.objective.spine_roi_tensor = spine_roi_tensor
# 2. 注入 Arrays (以防 objective 裡面偷偷用到 Numpy 陣列)
core.objective.image1_array = image1_array
core.objective.image2_array = image2_array
core.objective.image3_array = image3_array
# 3. 注入 Shapes (這就是導致這次 NoneType 報錯的真兇!)
core.objective.image2_shape = image2_shape # <--- 解除警報的最關鍵一行
core.objective.image_shape = image_shape
core.objective.shape = image_shape
# 4. 注入環境變數
core.objective.spacing = spacing
core.objective.device = device
core.objective.grid = grid
# 5. 注入尺寸參數 (兼容固定尺寸模式)
if not optimize_size:
core.objective.diameter = diameter
core.objective.length = length
# ==============================================================
# 建立明確的優化上下文(取代舊的跨檔案 global 注入;狀態全部顯式傳入目標函數)
ctx = OptimizationContext(
cortical_tensor=cortical_tensor,
spine_tensor=spine_tensor,
spine_roi_tensor=spine_roi_tensor,
image1_array=image1_array,
image2_array=image2_array,
image3_array=image3_array,
image2_shape=image2_shape,
spacing=spacing,
device=device,
grid=grid,
diameter=diameter if not optimize_size else None,
length=length if not optimize_size else None,
)
objective_fn = make_objective_function(ctx)
azi = azimuth_rotation(image2_path)
res = analyze_vertebral_tilt_contour(image2_path, edge_type='superior', show_plot=False, debug=False)
@ -828,9 +971,11 @@ def run_de_torch(
y_bounds = (image_shape[1]/5, image_shape[1]/2 - 1)
x_bounds_right = (image_shape[2]/2 + image_shape[2]/10, image_shape[2] - 1)
x_bounds_left = (0, image_shape[2]/2 - image_shape[2]/10 - 1)
azimuth_bounds_l = ((95-azi), (145-azi))
azimuth_bounds_r = ((50-azi), (85-azi))
altitude_bounds = ((60-alt), (75-alt))
# CBT 參數依據 references/Santoni 2009 (Spine J 9:366) 冠狀面 25-30° cranial (caudo-cephalad)、
# 軸狀面自正中線向外 (medial→lateral) ≤30°Delgado-Fernandez 2017 (ASJ 11:817)、Kim 2022 (SSRR 6:1)
azimuth_bounds_l = ((98-azi), (120-azi))
azimuth_bounds_r = ((60-azi), (82-azi))
altitude_bounds = ((60-alt), (70-alt))
else:
z_bounds = (0, image_shape[0] - 1)
y_bounds = (image_shape[1]/5, image_shape[1]/2 - 1)
@ -877,7 +1022,7 @@ def run_de_torch(
# --- 左側最佳化 ---
print("\n=== 左側 (DE) ===")
res_l = differential_evolution(objective_function, bounds_l, popsize=de_popsize, maxiter=max_iter)
res_l = differential_evolution(objective_fn, bounds_l, popsize=de_popsize, maxiter=max_iter)
position_l, loss_l = res_l.x, res_l.fun
overlap_l, diameter_l, length_l = eval_overlap_from_position(position_l, "L", optimize_size, spine_tensor, image_shape, spacing)
@ -886,7 +1031,7 @@ def run_de_torch(
"""
retries = 0
while (best_loss_l > 0 or best_overlap_l < OVERLAP_THRESH) and retries < 10:
res_l = differential_evolution(objective_function, bounds_l, popsize=de_popsize, maxiter=max_iter)
res_l = differential_evolution(objective_fn, bounds_l, popsize=de_popsize, maxiter=max_iter)
position_l, loss_l = res_l.x, res_l.fun
overlap_l, diameter_l, length_l = eval_overlap_from_position(position_l, "L", optimize_size, spine_tensor, image_shape, spacing)
@ -899,7 +1044,7 @@ def run_de_torch(
"""
# --- 右側最佳化 ---
print("\n=== 右側 (DE) ===")
res_r = differential_evolution(objective_function, bounds_r, popsize=de_popsize, maxiter=max_iter)
res_r = differential_evolution(objective_fn, bounds_r, popsize=de_popsize, maxiter=max_iter)
position_r, loss_r = res_r.x, res_r.fun
overlap_r, diameter_r, length_r = eval_overlap_from_position(position_r, "R", optimize_size, spine_tensor, image_shape, spacing)
@ -908,7 +1053,7 @@ def run_de_torch(
"""
retries = 0
while (best_loss_r > 0 or best_overlap_r < OVERLAP_THRESH) and retries < 10:
res_r = differential_evolution(objective_function, bounds_r, popsize=de_popsize, maxiter=max_iter)
res_r = differential_evolution(objective_fn, bounds_r, popsize=de_popsize, maxiter=max_iter)
position_r, loss_r = res_r.x, res_r.fun
overlap_r, diameter_r, length_r = eval_overlap_from_position(position_r, "R", optimize_size, spine_tensor, image_shape, spacing)
@ -969,34 +1114,22 @@ def run_nm_torch(
cortical_tensor = torch.from_numpy(image1_array).to(device=device, dtype=torch.uint8)
spine_tensor = torch.from_numpy(image2_array).to(device=device, dtype=torch.uint8)
spine_roi_tensor = torch.from_numpy(image3_array).to(device=device, dtype=torch.uint8)
# ================= [跨檔案注入變數:終極防呆版] =================
import core.objective
# 1. 注入 Tensors
core.objective.cortical_tensor = cortical_tensor
core.objective.spine_tensor = spine_tensor
core.objective.spine_roi_tensor = spine_roi_tensor
# 2. 注入 Arrays (以防 objective 裡面偷偷用到 Numpy 陣列)
core.objective.image1_array = image1_array
core.objective.image2_array = image2_array
core.objective.image3_array = image3_array
# 3. 注入 Shapes (這就是導致這次 NoneType 報錯的真兇!)
core.objective.image2_shape = image2_shape # <--- 解除警報的最關鍵一行
core.objective.image_shape = image_shape
core.objective.shape = image_shape
# 4. 注入環境變數
core.objective.spacing = spacing
core.objective.device = device
core.objective.grid = grid
# 5. 注入尺寸參數 (兼容固定尺寸模式)
if not optimize_size:
core.objective.diameter = diameter
core.objective.length = length
# ==============================================================
# 建立明確的優化上下文(取代舊的跨檔案 global 注入;狀態全部顯式傳入目標函數)
ctx = OptimizationContext(
cortical_tensor=cortical_tensor,
spine_tensor=spine_tensor,
spine_roi_tensor=spine_roi_tensor,
image1_array=image1_array,
image2_array=image2_array,
image3_array=image3_array,
image2_shape=image2_shape,
spacing=spacing,
device=device,
grid=grid,
diameter=diameter if not optimize_size else None,
length=length if not optimize_size else None,
)
objective_fn = make_objective_function(ctx)
azi = azimuth_rotation(image2_path)
res = analyze_vertebral_tilt_contour(image2_path, edge_type='superior', show_plot=False, debug=False)
@ -1007,9 +1140,11 @@ def run_nm_torch(
y_bounds = (image_shape[1]/5, image_shape[1]/2 - 1)
x_bounds_right = (image_shape[2]/2 + image_shape[2]/10, image_shape[2] - 1)
x_bounds_left = (0, image_shape[2]/2 - image_shape[2]/10 - 1)
azimuth_bounds_l = ((95-azi), (145-azi))
azimuth_bounds_r = ((50-azi), (85-azi))
altitude_bounds = ((60-alt), (75-alt))
# CBT 參數依據 references/Santoni 2009 (Spine J 9:366) 冠狀面 25-30° cranial (caudo-cephalad)、
# 軸狀面自正中線向外 (medial→lateral) ≤30°Delgado-Fernandez 2017 (ASJ 11:817)、Kim 2022 (SSRR 6:1)
azimuth_bounds_l = ((98-azi), (120-azi))
azimuth_bounds_r = ((60-azi), (82-azi))
altitude_bounds = ((60-alt), (70-alt))
else:
z_bounds = (0, image_shape[0] - 1)
y_bounds = (image_shape[1]/5, image_shape[1]/2 - 1)
@ -1054,7 +1189,7 @@ def run_nm_torch(
# --- 左側最佳化 ---
print("\n=== 左側 (Nelder-Mead) ===")
x0_l = get_random_x0(bounds_l)
res_l = minimize(objective_function, x0_l, method='Nelder-Mead', bounds=bounds_l, options={'maxiter': max_iter})
res_l = minimize(objective_fn, x0_l, method='Nelder-Mead', bounds=bounds_l, options={'maxiter': max_iter})
position_l, loss_l = res_l.x, res_l.fun
overlap_l, diameter_l, length_l = eval_overlap_from_position(position_l, "L", optimize_size, spine_tensor, image_shape, spacing)
@ -1064,7 +1199,7 @@ def run_nm_torch(
retries = 0
while (best_loss_l > 0 or best_overlap_l < OVERLAP_THRESH) and retries < 10:
x0_l = get_random_x0(bounds_l) # 每次 retry 都換一個隨機起始點
res_l = minimize(objective_function, x0_l, method='Nelder-Mead', bounds=bounds_l, options={'maxiter': max_iter})
res_l = minimize(objective_fn, x0_l, method='Nelder-Mead', bounds=bounds_l, options={'maxiter': max_iter})
position_l, loss_l = res_l.x, res_l.fun
overlap_l, diameter_l, length_l = eval_overlap_from_position(position_l, "L", optimize_size, spine_tensor, image_shape, spacing)
@ -1078,7 +1213,7 @@ def run_nm_torch(
# --- 右側最佳化 ---
print("\n=== 右側 (Nelder-Mead) ===")
x0_r = get_random_x0(bounds_r)
res_r = minimize(objective_function, x0_r, method='Nelder-Mead', bounds=bounds_r, options={'maxiter': max_iter})
res_r = minimize(objective_fn, x0_r, method='Nelder-Mead', bounds=bounds_r, options={'maxiter': max_iter})
position_r, loss_r = res_r.x, res_r.fun
overlap_r, diameter_r, length_r = eval_overlap_from_position(position_r, "R", optimize_size, spine_tensor, image_shape, spacing)
@ -1088,7 +1223,7 @@ def run_nm_torch(
retries = 0
while (best_loss_r > 0 or best_overlap_r < OVERLAP_THRESH) and retries < 10:
x0_r = get_random_x0(bounds_r)
res_r = minimize(objective_function, x0_r, method='Nelder-Mead', bounds=bounds_r, options={'maxiter': max_iter})
res_r = minimize(objective_fn, x0_r, method='Nelder-Mead', bounds=bounds_r, options={'maxiter': max_iter})
position_r, loss_r = res_r.x, res_r.fun
overlap_r, diameter_r, length_r = eval_overlap_from_position(position_r, "R", optimize_size, spine_tensor, image_shape, spacing)

View file

@ -36,10 +36,12 @@ def cl_score_torch_xfr(
# if in_bone == 0:
# return float(not_in_bone*200)
score += 10 * in_bone # 10 實在太低
score += 20 * in_bone # 10 實在太低
score += 100 * overlap
score -= 2000 * max(0, not_in_bone-10)
score -= 1000 * max(0, null_vox2-10)
# score -= 2000 * max(0, not_in_bone-10)
# score -= 1000 * max(0, null_vox2-10)
score -= 1000 * not_in_bone
score -= 1000 * null_vox2
return float(-score)

View file

@ -1,8 +1,309 @@
import numpy as np
import SimpleITK as sitk
from scipy.ndimage import center_of_mass
from scipy.ndimage import center_of_mass, rotate
import matplotlib.pyplot as plt
def _best_vertical_split(mask2d):
"""
binary 2D 陣列最後一軸 = x找讓 mask 與其鏡射重疊最大的垂直線 x = t
c[s] = Σ_u A[u]·A[s-u] 是每列自卷積批次 FFT 一次算出所有 s
回傳 (score, s_best)s = 2·tt 可能為半整數
"""
n = mask2d.shape[-1]
flat = np.asarray(mask2d).reshape(-1, n)
rows = flat[flat.max(axis=1) > 0]
if rows.size == 0:
return 0.0, 0
L = 1 << (2 * n - 1).bit_length()
padded = np.zeros((rows.shape[0], L), dtype=np.float32)
padded[:, :n] = rows.astype(np.float32)
F = np.fft.rfft(padded, axis=1)
conv = np.fft.irfft(F * F, axis=1)[:, :2 * n - 1]
score = np.clip(conv.sum(axis=0), 0, None)
s_best = int(np.argmax(score))
return float(score[s_best]), s_best
def best_symmetry_axis_angle(proj, coarse_step=10.0, fine_step=1.0):
"""
2D binary 投影axis0=row y, axis1=col x的左右鏡稱軸搜尋
將影像旋轉 θ 鏡稱軸變成垂直線col = const _best_vertical_split 評分
粗搜 0..180°coarse_step再在 winner 附近細搜fine_step
回傳 (theta_deg, score, s_best)
"""
base = (np.asarray(proj) > 0).astype(np.float32)
best_th, best, best_s = 0.0, -1.0, 0
for th in np.arange(0.0, 180.0, coarse_step):
sc, s = _best_vertical_split(rotate(base, th, reshape=False, order=0) > 0.5)
if sc > best:
best_th, best, best_s = float(th), sc, s
for th in np.arange(best_th - coarse_step, best_th + coarse_step, fine_step):
th2 = float(th) % 180.0
sc, s = _best_vertical_split(rotate(base, th2, reshape=False, order=0) > 0.5)
if sc > best:
best_th, best, best_s = th2, sc, s
return best_th, best, best_s
def _mirror_hit_count(X, Y, Z, n, d, m, sz, sy, sx):
"""每個骨 voxel 對平面 n·p=d 鏡射後四捨五入到最近 voxel回傳命中骨 voxel 的數量"""
nx, ny, nz = n
dist = X * nx + Y * ny + Z * nz - d
rx = (X - 2.0 * dist * nx).round().astype(np.int32)
ry = (Y - 2.0 * dist * ny).round().astype(np.int32)
rz = (Z - 2.0 * dist * nz).round().astype(np.int32)
ok = (rx >= 0) & (rx < sx) & (ry >= 0) & (ry < sy) & (rz >= 0) & (rz < sz)
if not ok.any():
return 0
return int(m[rz[ok], ry[ok], rx[ok]].sum())
def best_symmetry_plane(mask_zyx, phi_max=45.0, subsample=7,
coarse_step=7.5, fine_step=1.0):
"""
3D bone mask (z, y, x) 的最佳鏡稱面一般平面方程 a·x + b·y + c·z = d
voxel index 座標(a,b,c) 為單位法線方向任意不限制平行 YZ
每個 bone voxel 鏡射後四捨五入到最近 voxel 的命中率為分數
參數化 n = R_y(phi)·R_z(theta)·(1,0,0)
theta : 法線在 axial (x,y) 平面內的旋轉
phi : 法線出平面的傾斜限制在 [-phi_max, +phi_max] 以確保仍切分左右
搜尋theta 2D axial 投影粗定位 3D 三段式微細
/細階段用等距子樣 voxel 加速
回傳 dict
plane : (a, b, c, d) -> a*x + b*y + c*z = d
normal : (a, b, c)
offset : d
theta_deg / phi_deg : 法線參數
ratio : 鏡射命中率0..1
u, v : 平面內兩個正交方向供繪製用
"""
m = np.asarray(mask_zyx) > 0
sz, sy, sx = m.shape
zz, yy, xx = np.nonzero(m)
if xx.size < 100:
n = np.array([1.0, 0.0, 0.0])
d = (sx - 1) / 2.0
return {'plane': (1.0, 0.0, 0.0, float(d)), 'normal': (1.0, 0.0, 0.0),
'offset': float(d), 'theta_deg': 0.0, 'phi_deg': 0.0,
'ratio': 1.0, 'u': (0.0, 1.0, 0.0), 'v': (0.0, 0.0, 1.0)}
xf = xx.astype(np.float32)
yf = yy.astype(np.float32)
zf = zz.astype(np.float32)
N = xf.size
c0 = np.array([(sx - 1) / 2.0, (sy - 1) / 2.0, (sz - 1) / 2.0])
Xs, Ys, Zs = xf[::subsample], yf[::subsample], zf[::subsample]
def n_of(theta_deg, phi_deg):
t = np.deg2rad(theta_deg)
p = np.deg2rad(phi_deg)
return np.array([np.cos(t) * np.cos(p), np.sin(t), -np.cos(t) * np.sin(p)])
# theta 初值2D axial 投影搜尋(垂直面情形)
proj = m.max(axis=0)
theta0 = best_symmetry_axis_angle(proj.astype(np.float32))[0] if proj.sum() >= 10 else 0.0
best = None
def consider(theta, phi, d, full=False):
nonlocal best
n = n_of(theta, phi)
X, Y, Z = (xf, yf, zf) if full else (Xs, Ys, Zs)
s = _mirror_hit_count(X, Y, Z, n, d, m, sz, sy, sx)
if best is None or s > best['score']:
best = {'score': s, 'theta': float(theta), 'phi': float(phi), 'd': float(d)}
# stage 1粗搜尋子樣
for th in np.arange(theta0 - coarse_step * 2, theta0 + coarse_step * 2 + 1e-9, coarse_step):
for ph in np.arange(-phi_max, phi_max + 1e-9, coarse_step):
n = n_of(th, ph)
d0 = float(n @ c0)
for dd in (-10.0, 0.0, 10.0):
consider(th, ph, d0 + dd)
# stage 2細搜尋子樣
for th in np.arange(best['theta'] - 2 * fine_step * 2, best['theta'] + 2 * fine_step * 2 + 1e-9, fine_step):
for ph in np.arange(best['phi'] - 2 * fine_step * 2, best['phi'] + 2 * fine_step * 2 + 1e-9, fine_step):
for dd in (-3.0, -1.0, 0.0, 1.0, 3.0):
consider(th, ph, best['d'] + dd)
# stage 3微細搜尋全分辨率
for th in np.arange(best['theta'] - fine_step, best['theta'] + fine_step + 1e-9, fine_step / 2):
for ph in np.arange(best['phi'] - fine_step, best['phi'] + fine_step + 1e-9, fine_step / 2):
for dd in (-1.0, -0.5, 0.0, 0.5, 1.0):
consider(th, ph, best['d'] + dd, full=True)
# stage 4d 微調(全分辨率)
b = best
for dd in np.arange(-1.0, 1.0 + 1e-9, 0.25):
consider(b['theta'], b['phi'], b['d'] + dd, full=True)
n = n_of(best['theta'], best['phi'])
theta = best['theta']
d = best['d']
if theta > 90.0 or theta < -90.0: # 正規化到 (-90, 90],法線翻轉時 d 取反
theta -= 180.0
n = -n
d = -d
ratio = _mirror_hit_count(xf, yf, zf, n, d, m, sz, sy, sx) / N
u = np.cross(n, [0.0, 0.0, 1.0])
if np.linalg.norm(u) < 0.1:
u = np.cross(n, [1.0, 0.0, 0.0])
u = u / np.linalg.norm(u)
v = np.cross(n, u)
return {
'plane': (float(n[0]), float(n[1]), float(n[2]), float(d)),
'normal': (float(n[0]), float(n[1]), float(n[2])),
'offset': float(d),
'theta_deg': float(theta),
'phi_deg': float(best['phi']),
'ratio': float(ratio),
'u': (float(u[0]), float(u[1]), float(u[2])),
'v': (float(v[0]), float(v[1]), float(v[2])),
}
def segment_spinous_process(mask_zyx, sym, band_frac=0.06, min_band=6.0,
min_mass_frac=0.05):
"""
best_symmetry_plane 的結果 sym 3D bone mask (z, y, x) 切出棘突
棘突是中線後側構造利用鏡稱面 a·x+b·y+c·z=d 定義
1) 中線帶 voxel 到平面的有號距離 |s| <= w
w = max(min_band, band_frac * s 全寬)
2) 前後方向平面內兩軸 (u, v) |y| 分量大者
正規化成 +AP = 後側本資料系 y 往前遞增後側 = y 小側
3) 中線帶的 AP 分佈呈兩大叢椎體在前椎弓/棘突在後
以兩叢間的 AP 谷底為界AP >= 谷底 的中線帶 voxel = 棘突含中線椎弓
無明顯谷底如骨橋fallback 取中線帶後側 15%
回傳 (sp_mask (z,y,x) bool, ap_thresh, info dict)
資料過少時 sp_mask = Noneinfo['mode'] 說明原因
"""
m = np.asarray(mask_zyx) > 0
zz, yy, xx = np.nonzero(m)
info = {'n_bone': int(zz.size), 'n_sp': 0, 'ap_thresh': None,
'band_w': None, 'mode': 'empty'}
if zz.size < 50:
return None, None, info
a, b, c, d = sym['plane']
X = xx.astype(np.float64)
Y = yy.astype(np.float64)
Z = zz.astype(np.float64)
s = X * a + Y * b + Z * c - d
u = np.array(sym['u'])
v = np.array(sym['v'])
u_ap = u if abs(u[1]) >= abs(v[1]) else v
if u_ap[1] > 0:
u_ap = -u_ap # +AP = 後側y 小側)
w = max(float(min_band), float(band_frac) * float(s.max() - s.min()))
mid = np.abs(s) <= w
ap = X * u_ap[0] + Y * u_ap[1] + Z * u_ap[2]
aps = ap[mid]
info['band_w'] = float(w)
if aps.size < 50:
info['mode'] = 'too_few_midline'
return None, None, info
lo = int(np.floor(aps.min()))
hi = int(np.ceil(aps.max()))
th = None
mode = 'fallback'
if hi - lo >= 10:
hist, edges = np.histogram(aps, bins=range(lo, hi + 1))
csum = np.concatenate([[0], np.cumsum(hist)])
total = csum[-1]
peak = hist.max()
best_i, best_score = None, -1.0
for i in range(len(hist)):
if hist[i] >= 0.05 * peak:
continue
if csum[i] < min_mass_frac * total or (total - csum[i + 1]) < min_mass_frac * total:
continue
score = min(csum[i], total - csum[i + 1])
if score > best_score:
best_score, best_i = score, i
if best_i is not None:
th = float(0.5 * (edges[best_i] + edges[best_i + 1]))
mode = 'gap'
if th is None:
th = float(np.quantile(aps, 0.85))
sp_mask = np.zeros(m.shape, dtype=bool)
sel = mid & (ap >= th)
sp_mask[zz[sel], yy[sel], xx[sel]] = True
info.update(n_sp=int(sel.sum()), ap_thresh=th, mode=mode)
return sp_mask, th, info
def best_upper_endplate_plane(mask_zyx, angle_max=45.0, thresh=3.0,
n_iter=500, seed=42):
"""
3D bone mask (z, y, x) 的最佳上終板近似平面 a·x + b·y + c·z = d
voxel index 座標(a,b,c) 為朝上的單位法線
1) 每個 (y, x) 欄位取最上方 bone voxel 作為頂面點僅前側半邊
y >= COM_y避開後方元素 2D superior endplate 定義一致
2) RANSAC 三點擬平面法線限制在與 +z angle_max°
計數 ±thresh voxel 內的頂面點為 inlier inlier 最多者
3) SVD 最小二乘微調
回傳 dict資料不足時回傳 None
plane : (a, b, c, d)
normal / offset
tilt_deg : 法線與 +z 軸的夾角上終板傾斜
inlier_ratio : 頂面點落在平面 ±thresh 的比例
n_points / n_inliers
u, v : 平面內正交方向供繪製用
"""
m = np.asarray(mask_zyx) > 0
nz, ny, nx = m.shape
idx = np.where(m, np.arange(nz)[:, None, None], -1)
ztop = idx.max(axis=0) # (y, x) 每欄最上 z
y_split = int(round(center_of_mass(m)[1])) if m.sum() else 0
# ztop 是 (y, x):條件作用在 y 軸axis 0
sel = (ztop >= 0) & (np.arange(ny)[:, None] >= y_split)
yy, xx = np.where(sel)
if xx.size < 8:
return None
P = np.stack((xx, yy, ztop[yy, xx]), axis=1).astype(np.float64)
n = P.shape[0]
rng = np.random.default_rng(seed)
cos_min = np.cos(np.deg2rad(angle_max))
best_cnt, best_nv, best_d = -1, None, 0.0
for _ in range(n_iter):
i, j, k = rng.choice(n, 3, replace=False)
cr = np.cross(P[j] - P[i], P[k] - P[i])
ln = np.linalg.norm(cr)
if ln < 1e-6:
continue
nv = cr / ln
if nv[2] < 0:
nv = -nv
if nv[2] < cos_min: # 法線必須朝上
continue
d = float(nv @ P[i])
cnt = int(np.count_nonzero(np.abs(P @ nv - d) <= thresh))
if cnt > best_cnt:
best_cnt, best_nv, best_d = cnt, nv, d
if best_nv is None:
return None
# SVD 微調
inl = P[np.abs(P @ best_nv - best_d) <= thresh]
if inl.shape[0] < 3:
return None
mean = inl.mean(axis=0)
_, _, Vt = np.linalg.svd(inl - mean, full_matrices=False)
nv = Vt[2]
if nv[2] < 0:
nv = -nv
d = float(nv @ mean)
dist = np.abs(P @ nv - d)
inl = P[dist <= thresh]
u = np.cross(nv, [1.0, 0.0, 0.0])
u = u / np.linalg.norm(u)
v = np.cross(nv, u)
return {
'plane': (float(nv[0]), float(nv[1]), float(nv[2]), d),
'normal': (float(nv[0]), float(nv[1]), float(nv[2])),
'offset': d,
'tilt_deg': float(np.degrees(np.arccos(np.clip(nv[2], -1.0, 1.0)))),
'inlier_ratio': float(inl.shape[0] / n),
'n_points': int(n),
'n_inliers': int(inl.shape[0]),
'u': (float(u[0]), float(u[1]), float(u[2])),
'v': (float(v[0]), float(v[1]), float(v[2])),
}
def azimuth_rotation(image, show_plt=False, save_plt=False, output_path=None):
img = sitk.ReadImage(image, sitk.sitkUInt8)
@ -55,6 +356,23 @@ def azimuth_rotation(image, show_plt=False, save_plt=False, output_path=None):
plt.plot([x_center, cx], [y_min, cy], 'c-', lw=2,
label=f'Angle with y-axis: {angle_deg:.1f}°')
# 中矢狀面:最佳鏡稱面 a·x + b·y + c·z = d法線方向任意不平行 YZ 面)
# 畫該平面在體積中央 z 切片上的截線
sym3 = best_symmetry_plane(arr_zyx)
a3, b3, c3, d3 = sym3['plane']
zc_ = (arr_zyx.shape[0] - 1) / 2.0
rhs_ = d3 - c3 * zc_ # a*x + b*y = rhs
n2d = np.hypot(a3, b3)
x0_ = a3 * rhs_ / (n2d * n2d)
y0_ = b3 * rhs_ / (n2d * n2d)
u2_ = np.array([b3, -a3]) / n2d
tfg_ = (xs - x0_) * u2_[0] + (ys - y0_) * u2_[1]
L_ = float(np.abs(tfg_).max())
plt.plot([x0_ - L_ * u2_[0], x0_ + L_ * u2_[0]],
[y0_ - L_ * u2_[1], y0_ + L_ * u2_[1]],
color='magenta', lw=2, linestyle='--',
label=f'Mirror plane: {a3:+.2f}x {b3:+.2f}y {c3:+.2f}z = {d3:.1f}')
plt.legend()
plt.title("Top point + centroid-directed line")
plt.axis("off")

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@ -1,6 +1,9 @@
import torch
import numpy as np
import matplotlib.pyplot as plt
from matplotlib.colors import to_rgba
from matplotlib.lines import Line2D
from mpl_toolkits.mplot3d.art3d import Poly3DCollection
import os
from datetime import datetime
import csv
@ -8,9 +11,20 @@ import csv
from core.cylinder import generate_cylinder_n_torch, generate_cylinder_o_torch, snap_to_discrete_values
from core.intersection import center_line_intersections_torch
from core.scoring import cl_score_torch, compute_overlap_ratio_from_cylinder_mask, cl_score_torch_xfr
from imaging.orientation import azimuth_rotation, analyze_vertebral_tilt_contour
from imaging.orientation import (azimuth_rotation, analyze_vertebral_tilt_contour,
best_symmetry_plane, best_upper_endplate_plane,
segment_spinous_process)
from utils.helpers import save_with_unique_name
# Volume absorption 渲染Beer-Lambert每 voxel 不透明度 = 1 - exp(-mu * voxel_width)
# 骨頭核心厚度達 70-90 voxel沿視線堆疊會使任何 per-voxel alpha 累積成不透明。
# 因此以「抽稀 (SUBSAMPLE) 降低堆疊數量」+「低 mu 控制每點吸收」兩項共同調出淡薄 X-ray 陰影,
# 同時保留皮質 / 鬆質的吸收入射差異mu 比值)。
BONE_MU_CORTICAL = 0.02 # 1/mm → 每 voxel = 1-exp(-0.02*0.5) ~ 0.010
BONE_MU_TRABECULAR = 0.005 # 1/mm → 每 voxel = 1-exp(-0.005*0.5) ~ 0.0025
BONE_MARKER_SIZE = 3.0 # 骨骼散點點面積 (pt^2);略大以補償抽稀後的顆粒感
BONE_SUBSAMPLE = 1 # 每 10 個骨 voxel 畫 1 個降低堆疊不透明度1=全畫)
def set_axes_equal_3d(ax):
"""
Make axes of 3D plot have equal scale so that spheres appear as spheres,
@ -165,55 +179,171 @@ def res_plt_2_torch(
z_cyl_r1, y_cyl_r1, x_cyl_r1 = np.where(cyl_r_cpu == 1)
z_cyl_r2, y_cyl_r2, x_cyl_r2 = np.where(cyl_ro_cpu == 1)
z_img, y_img, x_img = np.where(spine_cpu == 1)
# 骨頭 voxel 依「體積吸收」分成兩組:皮質(高不透明度)與鬆質(低不透明度)
cortical_cpu = cortical_tensor.cpu().numpy()
voxel_mm = float(spacing[0])
alpha_cortical = 1.0 - np.exp(-BONE_MU_CORTICAL * voxel_mm)
alpha_trabecular = 1.0 - np.exp(-BONE_MU_TRABECULAR * voxel_mm)
z_corti, y_corti, x_corti = np.where((spine_cpu == 1) & (cortical_cpu == 1))
z_trab, y_trab, x_trab = np.where((spine_cpu == 1) & (cortical_cpu == 0))
# 中矢狀面:骨頭的最佳鏡稱面,一般平面 a·x + b·y + c·z = d法線方向任意
sym = best_symmetry_plane(spine_cpu)
# 棘突:鏡稱面中線帶(|s|<=w且在 AP 谷底之後側的骨 voxel換不同顏色標示
sp_mask, sp_th, sp_info = segment_spinous_process(spine_cpu, sym)
if sp_mask is not None and sp_mask.any():
sp_corti = sp_mask[z_corti, y_corti, x_corti]
sp_trab = sp_mask[z_trab, y_trab, x_trab]
sp_n_bone = max(int(spine_cpu.sum()), 1)
print(f"[SPINOUS] n={sp_info['n_sp']} "
f"({100.0 * sp_info['n_sp'] / sp_n_bone:.1f}% of bone) "
f"band=+/-{sp_info['band_w']:.1f} voxel AP>={sp_info['ap_thresh']:.1f} "
f"mode={sp_info['mode']}")
else:
sp_corti = sp_trab = None
# X-ray 外觀:骨頭合成一個半透明體積吸收點雲(下方);
# 螺絲(中心線 + 圓柱 + 入口軌跡延长)合成一個全不透明點雲,永遠畫在骨頭之上
def _rgba_block(n, color, a):
arr = np.empty((n, 4))
arr[:] = to_rgba(color)
arr[:, 3] = a
return arr
x_bone = np.concatenate([x_corti, x_trab])
y_bone = np.concatenate([y_corti, y_trab])
z_bone = np.concatenate([z_corti, z_trab])
bone_rgba = np.concatenate([
_rgba_block(len(x_corti), 'lightblue', float(alpha_cortical)),
_rgba_block(len(x_trab), 'lightblue', float(alpha_trabecular)),
])
bone_size = np.full(len(x_bone), BONE_MARKER_SIZE)
# 抽稀:降低堆疊不透明度以呈現淡薄 X-ray 陰影
if BONE_SUBSAMPLE > 1:
x_bone = x_bone[::BONE_SUBSAMPLE]
y_bone = y_bone[::BONE_SUBSAMPLE]
z_bone = z_bone[::BONE_SUBSAMPLE]
bone_rgba = bone_rgba[::BONE_SUBSAMPLE]
bone_size = bone_size[::BONE_SUBSAMPLE]
if sp_corti is not None:
sp_flag = np.concatenate([sp_corti, sp_trab])
if BONE_SUBSAMPLE > 1:
sp_flag = sp_flag[::BONE_SUBSAMPLE]
bone_rgba[sp_flag] = to_rgba('purple', 0.95)
x_screw = np.concatenate([x_lin1, x_lin2, x_cyl_l1, x_cyl_l2, x_cyl_r1, x_cyl_r2])
y_screw = np.concatenate([y_lin1, y_lin2, y_cyl_l1, y_cyl_l2, y_cyl_r1, y_cyl_r2])
z_screw = np.concatenate([z_lin1, z_lin2, z_cyl_l1, z_cyl_l2, z_cyl_r1, z_cyl_r2])
_a, _b, _c, _d = sym['plane']
_n = np.array([_a, _b, _c])
_u = np.array(sym['u'])
_v = np.array(sym['v'])
_p0 = _d * _n # 平面上最接近原點的點
xyz_bone = np.stack([x_bone - _p0[0], y_bone - _p0[1], z_bone - _p0[2]], axis=1)
_pu = xyz_bone @ _u
_pv = xyz_bone @ _v
_U_, _V_ = np.meshgrid(np.linspace(_pu.min(), _pu.max(), 8),
np.linspace(_pv.min(), _pv.max(), 8))
_Xp = _p0[0] + _U_ * _u[0] + _V_ * _v[0]
_Yp = _p0[1] + _U_ * _u[1] + _V_ * _v[1]
_Zp = _p0[2] + _U_ * _u[2] + _V_ * _v[2]
# 上終板平面RANSAC 擬合骨頭頂面(前側)的最佳 a·x + b·y + c·z = d
symp = best_upper_endplate_plane(spine_cpu)
_EX = _EY = _EZ = None
if symp is not None:
_ea, _eb, _ec, _ed = symp['plane']
_en = np.array([_ea, _eb, _ec])
_eu = np.array(symp['u'])
_ev = np.array(symp['v'])
_ep0 = _ed * _en
xz_ep = np.stack([x_bone - _ep0[0], y_bone - _ep0[1], z_bone - _ep0[2]], axis=1)
_pu_ep = xz_ep @ _eu
_pv_ep = xz_ep @ _ev
_EU, _EV = np.meshgrid(np.linspace(_pu_ep.min(), _pu_ep.max(), 8),
np.linspace(_pv_ep.min(), _pv_ep.max(), 8))
_EX = _ep0[0] + _EU * _eu[0] + _EV * _ev[0]
_EY = _ep0[1] + _EU * _eu[1] + _EV * _ev[1]
_EZ = _ep0[2] + _EU * _eu[2] + _EV * _ev[2]
screw_rgba = np.concatenate([
_rgba_block(len(x_lin1), 'r', 1.0),
_rgba_block(len(x_lin2), 'r', 1.0),
_rgba_block(len(x_cyl_l1), 'darkcyan', 1.0),
_rgba_block(len(x_cyl_l2), 'pink', 1.0),
_rgba_block(len(x_cyl_r1), 'blue', 1.0),
_rgba_block(len(x_cyl_r2), 'pink', 1.0),
])
screw_size = np.concatenate([
np.full(len(x_lin1), 3), np.full(len(x_lin2), 3),
np.full(len(x_cyl_l1), 36), np.full(len(x_cyl_l2), 36),
np.full(len(x_cyl_r1), 36), np.full(len(x_cyl_r2), 36),
])
fig = plt.figure(figsize=(12, 12))
# 圖例色塊提高到可讀不透明度(實際渲染仍用真實吸收 alpha
_leg_alpha_c = max(float(alpha_cortical), 0.35)
_leg_alpha_t = max(float(alpha_trabecular), 0.2)
legend_handles = [
Line2D([], [], marker='o', ls='', ms=5, color=to_rgba('lightblue', _leg_alpha_c), label='Spine (cortical)'),
Line2D([], [], marker='o', ls='', ms=5, color=to_rgba('lightblue', _leg_alpha_t), label='Spine (trabecular)'),
Line2D([], [], marker='o', ls='', ms=2, color='r', label='Centerline'),
Line2D([], [], marker='o', ls='', ms=6, color='darkcyan', label='Cylinder(L)'),
Line2D([], [], marker='o', ls='', ms=6, color='blue', label='Cylinder(R)'),
Line2D([], [], marker='o', ls='', ms=6, color='pink', label='Entry track (outer)'),
Line2D([], [], color='orange', lw=2, alpha=0.6,
label=f"Mirror plane {sym['plane'][0]:+.2f}x {sym['plane'][1]:+.2f}y {sym['plane'][2]:+.2f}z = {sym['plane'][3]:.1f}"),
]
if sp_corti is not None:
legend_handles.append(Line2D([], [], marker='o', ls='', ms=6, color='purple',
label=f"Spinous process (mirror-plane midline, {sp_info['n_sp']} vox)"))
if symp is not None:
legend_handles.append(Line2D([], [], color='green', lw=2, alpha=0.7,
label=f"Upper endplate plane tilt {symp['tilt_deg']:.1f} deg"))
def _fill_ax(ax):
# X-ray 外觀:關閉 mplot3d 依深度自動排序 zorder否則半透明骨頭會被重繪到
# 螺絲上方);改為固定分層:吸收骨頭 zorder=5全不透明螺絲 zorder=10
ax.computed_zorder = False
sc_bone = ax.scatter(x_bone, y_bone, z_bone, c=bone_rgba, s=bone_size, marker='o')
sc_bone.set_zorder(5)
sc_screw = ax.scatter(x_screw, y_screw, z_screw, c=screw_rgba, s=screw_size, marker='o')
sc_screw.set_zorder(10)
# 中矢狀面(理論左右對稱切分面):半透明橘色平面 x = x_mid
# 平面邊緣畫橘色線,讓 axial / 正視(側看時)也能清楚看到切分線
plane = ax.plot_surface(_Xp, _Yp, _Zp, color='orange', alpha=0.30,
linewidth=1.0, edgecolor='orange', rstride=1, cstride=1)
plane.set_zorder(8)
# 上終板平面:半透明綠色平面(邊緣綠線)
if _EX is not None:
ep = ax.plot_surface(_EX, _EY, _EZ, color='green', alpha=0.35,
linewidth=1.0, edgecolor='green', rstride=1, cstride=1)
ep.set_zorder(7)
ax1 = fig.add_subplot(221, projection='3d')
ax1.scatter(x_lin1, y_lin1, z_lin1, c='r', marker='o', s=1)
ax1.scatter(x_lin2, y_lin2, z_lin2, c='r', marker='o', s=1)
ax1.scatter(x_cyl_l1, y_cyl_l1, z_cyl_l1, c='darkcyan', marker='o', label='Cylinder(L)')
ax1.scatter(x_cyl_l2, y_cyl_l2, z_cyl_l2, c='pink', marker='o')
ax1.scatter(x_cyl_r1, y_cyl_r1, z_cyl_r1, c='blue', marker='o', label='Cylinder(R)')
ax1.scatter(x_cyl_r2, y_cyl_r2, z_cyl_r2, c='pink', marker='o')
ax1.scatter(x_img, y_img, z_img, c='lightblue', marker='+', alpha=0.04, label='Spine')
_fill_ax(ax1)
ax1.set_xlabel('X-axis'); ax1.set_ylabel('Y-axis'); ax1.set_zlabel('Z-axis')
set_axes_equal_3d(ax1)
ax2 = fig.add_subplot(222, projection='3d')
ax2.view_init(elev=90, azim=-90, roll=0)
ax2.scatter(x_lin1, y_lin1, z_lin1, c='r', marker='o', s=1)
ax2.scatter(x_lin2, y_lin2, z_lin2, c='r', marker='o', s=1)
ax2.scatter(x_cyl_l1, y_cyl_l1, z_cyl_l1, c='darkcyan', marker='o', label='Cylinder(L)')
ax2.scatter(x_cyl_l2, y_cyl_l2, z_cyl_l2, c='pink', marker='o')
ax2.scatter(x_cyl_r1, y_cyl_r1, z_cyl_r1, c='blue', marker='o', label='Cylinder(R)')
ax2.scatter(x_cyl_r2, y_cyl_r2, z_cyl_r2, c='pink', marker='o')
ax2.scatter(x_img, y_img, z_img, c='lightblue', marker='+', alpha=0.04, label='Spine')
_fill_ax(ax2)
ax2.set_xlabel('X-axis'); ax2.set_ylabel('Y-axis'); ax2.set_zlabel('Z-axis')
set_axes_equal_3d(ax2)
ax2.legend()
ax2.legend(handles=legend_handles)
ax3 = fig.add_subplot(223, projection='3d')
ax3.view_init(elev=0, azim=90, roll=0)
ax3.scatter(x_lin1, y_lin1, z_lin1, c='r', marker='o', s=1)
ax3.scatter(x_lin2, y_lin2, z_lin2, c='r', marker='o', s=1)
ax3.scatter(x_cyl_l1, y_cyl_l1, z_cyl_l1, c='darkcyan', marker='o', label='Cylinder(L)')
ax3.scatter(x_cyl_l2, y_cyl_l2, z_cyl_l2, c='pink', marker='o')
ax3.scatter(x_cyl_r1, y_cyl_r1, z_cyl_r1, c='blue', marker='o', label='Cylinder(R)')
ax3.scatter(x_cyl_r2, y_cyl_r2, z_cyl_r2, c='pink', marker='o')
ax3.scatter(x_img, y_img, z_img, c='lightblue', marker='+', alpha=0.04, label='Spine')
_fill_ax(ax3)
ax3.set_xlabel('X-axis'); ax3.set_ylabel('Y-axis'); ax3.set_zlabel('Z-axis')
set_axes_equal_3d(ax3)
ax4 = fig.add_subplot(224, projection='3d')
ax4.view_init(elev=0, azim=0, roll=0)
ax4.scatter(x_lin1, y_lin1, z_lin1, c='r', marker='o', s=1)
ax4.scatter(x_lin2, y_lin2, z_lin2, c='r', marker='o', s=1)
ax4.scatter(x_cyl_l1, y_cyl_l1, z_cyl_l1, c='darkcyan', marker='o', label='Cylinder(L)')
ax4.scatter(x_cyl_l2, y_cyl_l2, z_cyl_l2, c='pink', marker='o')
ax4.scatter(x_cyl_r1, y_cyl_r1, z_cyl_r1, c='blue', marker='o', label='Cylinder(R)')
ax4.scatter(x_cyl_r2, y_cyl_r2, z_cyl_r2, c='pink', marker='o')
ax4.scatter(x_img, y_img, z_img, c='lightblue', marker='+', alpha=0.04, label='Spine')
_fill_ax(ax4)
ax4.set_xlabel('X-axis'); ax4.set_ylabel('Y-axis'); ax4.set_zlabel('Z-axis')
set_axes_equal_3d(ax4)
@ -225,12 +355,12 @@ def res_plt_2_torch(
overlap_b_l = ((spine_tensor == 1) & (cyl_l == 1)).sum().item()
overlap_b_r = ((spine_tensor == 1) & (cyl_r == 1)).sum().item()
overlap_cortical_l = (overlap_l / cyl_points_l) * 100
overlap_cortical_r = (overlap_r / cyl_points_r) * 100
overlap_vertebral_l = (overlap_b_l / cyl_points_l) * 100
overlap_vertebral_r = (overlap_b_r / cyl_points_r) * 100
cb_ratio_l = overlap_cortical_l/overlap_vertebral_l
cb_ratio_r = overlap_cortical_r/overlap_vertebral_r
overlap_cortical_l = (overlap_l / cyl_points_l) * 100 if cyl_points_l else 0.0
overlap_cortical_r = (overlap_r / cyl_points_r) * 100 if cyl_points_r else 0.0
overlap_vertebral_l = (overlap_b_l / cyl_points_l) * 100 if cyl_points_l else 0.0
overlap_vertebral_r = (overlap_b_r / cyl_points_r) * 100 if cyl_points_r else 0.0
cb_ratio_l = overlap_cortical_l/overlap_vertebral_l if overlap_vertebral_l else 0.0
cb_ratio_r = overlap_cortical_r/overlap_vertebral_r if overlap_vertebral_r else 0.0
user_altitude_l = 90 - best_position_l[4] - alt
user_altitude_r = 90 - best_position_r[4] - alt
user_azimuth_l = 90 - best_position_l[3] - azi

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@ -1,4 +1,10 @@
import os
import re
import sys
import time
import queue as queue_module
import subprocess
import multiprocessing as mp
import SimpleITK as sitk
import torch
@ -15,6 +21,108 @@ azimuth_rotation_dir = '/mnt/1248/open2/cyrou/azimuth_rotation'
tilt_contour_dir = '/mnt/1248/open2/cyrou/tilt_contour'
Output_dir = '/mnt/1248/open/cyrou/Output'
LEVELS = ('L1', 'L2', 'L3', 'L4', 'L5')
LOG_DIR = os.path.join(os.path.dirname(os.path.abspath(__file__)), 'logs')
# 目前任務標記(每個 worker 流程各自一份),讓交錯的 log 可以歸屬到 (volume, level, side)
_TASK_TAG = {'vid': None, 'level': None, 'side': None}
_NP_WRAP_RE = re.compile(r'\bnp\.[A-Za-z_][A-Za-z0-9_]*\(([^()]*)\)')
def set_task_tag(volume_id, level):
_TASK_TAG['vid'] = volume_id
_TASK_TAG['level'] = level
_TASK_TAG['side'] = None
class _Tee:
"""同時輸出到 console 與 log 檔,逐行加上如 [0001 L1 LEFT] 的標記。
volume id 末段1.3.6.1.4.1.9328.50.4.0001 -> 0001
side [LEFT]/[RIGHT]/左側/右側 段落標記判定並沿用給後續行
最終結果段屬於整椎重置沿用值其中的 Left/Right 摘要行只標該行本身
np.float64(...) 之類包裹會解包成裸數值"""
def __init__(self, console, log_fh):
self.console = console
self.log_fh = log_fh
self.buf = ''
@staticmethod
def _marker_side(line):
"""回傳 (side, persist)[LEFT]/[RIGHT]/左側/右側 是段落標記persist=True
Left/Right 摘要行只標該行persist=False"""
s = line.lstrip()
if s.startswith('[LEFT]') or '左側' in s:
return 'LEFT', True
if s.startswith('[RIGHT]') or '右側' in s:
return 'RIGHT', True
if s.startswith('Left '):
return 'LEFT', False
if s.startswith('Right '):
return 'RIGHT', False
return None, False
def _prefix(self, side):
if not _TASK_TAG['vid'] or not _TASK_TAG['level']:
return ''
vol = _TASK_TAG['vid'].rsplit('.', 1)[-1]
tag = f'{vol} {_TASK_TAG["level"]}'
if side:
tag += f' {side}'
return f'[{tag}] '
def _emit(self, line):
line = _NP_WRAP_RE.sub(r'\1', line)
if '最終結果' in line:
_TASK_TAG['side'] = None
side, persist = self._marker_side(line)
if persist:
_TASK_TAG['side'] = side
eff_side = side if side is not None else _TASK_TAG['side']
prefix = self._prefix(eff_side) if line.strip() else ''
if prefix:
# 前綴已含 side 時,去掉行首重複的 [LEFT] / [RIGHT] 標記
marker = f'[{eff_side}] '
if line.startswith(marker):
line = line[len(marker):]
self.console.write(prefix + line + '\n')
self.log_fh.write(prefix + line + '\n')
def write(self, data):
if not data:
return
self.buf += data
while True:
idx_n = self.buf.find('\n')
idx_r = self.buf.find('\r')
candidates = [i for i in (idx_n, idx_r) if i != -1]
if not candidates:
break
idx = min(candidates)
self._emit(self.buf[:idx])
self.buf = self.buf[idx + 1:]
def flush(self):
if self.buf:
self._emit(self.buf)
self.buf = ''
self.console.flush()
self.log_fh.flush()
def isatty(self):
return False
def setup_tee(log_path):
"""把這個流程的 stdout/stderr 同時寫到 log_pathappend、line-buffered"""
log_fh = open(log_path, 'a', buffering=1)
sys.stdout = _Tee(sys.stdout, log_fh)
sys.stderr = _Tee(sys.stderr, log_fh)
def get_device(gpu_id=None):
if torch.cuda.is_available():
if gpu_id is None:
@ -22,7 +130,7 @@ def get_device(gpu_id=None):
gpu_id = 0
for i in range(torch.cuda.device_count()):
free_mem, _ = torch.cuda.mem_get_info(i)
# print(f'GPU {i}: {torch.cuda.get_device_name(i)} {free_mem}')
# print(f'GPU {gpu_id}: {torch.cuda.get_device_name(gpu_id)} {free_mem}')
if free_mem > max_free:
max_free = free_mem
gpu_id = i
@ -52,13 +160,14 @@ def debug_orientation(volume_id, level):
# print(f'Azimuth: {azi}, Alt: {alt}')
print(f'Alt: {alt}')
def debug_pso(volume_id, level):
def debug_pso(volume_id, level, device=None):
# ====== PSO ======
swarm_size = 100
max_iter = 100
# ====== DEVICE ======
device = get_device()
if device is None:
device = get_device()
# ====== OTHER ======
spacing = [0.5, 0.5, 0.5]
@ -79,6 +188,12 @@ def debug_pso(volume_id, level):
roi_array = sitk.GetArrayFromImage(roi_image)
image_shape = binary_array.shape
# 資料層級的快速失敗…9328.50.4.0653 L5 是 1-voxel 寬的退化體積)
if binary_array.sum() == 0:
raise ValueError(f'{volume_id} {level}: empty bone mask')
if min(image_shape) < 8:
raise ValueError(f'{volume_id} {level}: degenerate volume shape {image_shape}')
cortical_tensor = torch.tensor(cortical_array, device=device)
binary_tensor = torch.tensor(binary_array, device=device)
@ -112,6 +227,57 @@ def debug_pso(volume_id, level):
# exit()
def list_gpu_ids():
"""透過 nvidia-smi 取得 GPU ID主流程不初始化 CUDA避免污染 fork/spawn 子流程)"""
try:
out = subprocess.check_output(
['nvidia-smi', '--query-gpu=index', '--format=csv,noheader'],
text=True,
)
return [int(line.strip()) for line in out.splitlines() if line.strip()]
except Exception:
return []
def gpu_worker(gpu_id, log_path, task_queue, result_queue):
"""每張 GPU 一個工作流程:先鎖死該 GPU再從共享隊列領 (volume, level) 任務"""
# worker 是獨立流程,要自己把輸出 tee 到 log 檔
setup_tee(log_path)
# 必須在任何 torch.cuda 呼叫前設定
os.environ['CUDA_VISIBLE_DEVICES'] = str(gpu_id)
torch.cuda.set_device(0)
device = torch.device('cuda:0')
print(f'=== [GPU {gpu_id}] worker started ===', flush=True)
while True:
# 注意multiprocessing.Queue 沒有 task_done()(只有 queue.Queue 有),別加回來
item = task_queue.get()
if item is None:
break
volume_id, level = item
set_task_tag(volume_id, level)
try:
debug_pso(volume_id, level, device)
result_queue.put(('task', gpu_id, volume_id, level, True, ''))
except Exception as e:
print(f'[GPU {gpu_id}] Error in {volume_id} {level}: {e}', flush=True)
result_queue.put(('task', gpu_id, volume_id, level, False, str(e)))
result_queue.put(('done', gpu_id))
print(f'=== [GPU {gpu_id}] worker finished ===', flush=True)
def _run_sequential(tasks):
"""沒有或只有一張GPU 時的回退:單流程串行"""
device = get_device()
for volume_id, level in tasks:
set_task_tag(volume_id, level)
try:
debug_pso(volume_id, level, device)
except Exception as e:
print(f'Error in {volume_id} {level}: {e}')
def main():
# level = 'L1'
@ -121,38 +287,97 @@ def main():
# process_volume(volume_id, level)
# exit()
# 要處理的 volume 數(並行模式下是「最多嘗試的 volume 數」)
MAX_SUCCESSFUL_VOLUMES = 100
number_of_successful_volumes = 0
MAX_SUCCESSFUL_VOLUMES = 1
# for volume_id in (
# '1.3.6.1.4.1.9328.50.4.0001',
# '1.3.6.1.4.1.9328.50.4.0002',
# '1.3.6.1.4.1.9328.50.4.0003',
# '1.3.6.1.4.1.9328.50.4.0004',
# '1.3.6.1.4.1.9328.50.4.0005',
# # '1.3.6.1.4.1.9328.50.4.0006',
# ):
# log 檔console 與檔案同時輸出;各 GPU worker 也會 append 進同一個檔)
os.makedirs(LOG_DIR, exist_ok=True)
log_path = os.path.join(LOG_DIR, f'xfr_debug_{time.strftime("%Y%m%d_%H%M%S")}.log')
setup_tee(log_path)
print(f'Log file: {log_path}', flush=True)
print(f'Command: {sys.executable} {" ".join(sys.argv)}', flush=True)
print(f'Working directory: {os.getcwd()}', flush=True)
for volume_id in sorted(os.listdir(standardized_dir)):
# debug_orientation(volume_id, level)
error_flag = False
for level in ('L1', 'L2', 'L3', 'L4', 'L5'):
# for level in ('L5',):
# debug_orientation(volume_id, level)
try:
debug_pso(volume_id, level)
except Exception as e:
print(f'Error in {volume_id} {level}: {e}')
error_flag = True
continue
if not error_flag:
number_of_successful_volumes += 1
volumes = [d for d in sorted(os.listdir(standardized_dir))
if os.path.isdir(os.path.join(standardized_dir, d))]
volumes = volumes[:MAX_SUCCESSFUL_VOLUMES]
if number_of_successful_volumes >= MAX_SUCCESSFUL_VOLUMES:
tasks = [(vid, level) for vid in volumes for level in LEVELS]
print(f'Total {len(volumes)} volumes / {len(tasks)} (volume, level) tasks', flush=True)
gpu_ids = list_gpu_ids()
if len(gpu_ids) <= 1:
print(f'Only {len(gpu_ids)} GPU(s) available, running sequentially', flush=True)
_run_sequential(tasks)
return
print(f'Found {len(gpu_ids)} GPUs: {gpu_ids}, starting {len(gpu_ids)} workers (one per GPU)', flush=True)
ctx = mp.get_context('spawn')
task_queue = ctx.Queue()
result_queue = ctx.Queue()
for t in tasks:
task_queue.put(t)
for _ in gpu_ids:
task_queue.put(None) # 每個 worker 一個結束哨兵
procs = [ctx.Process(target=gpu_worker, args=(g, log_path, task_queue, result_queue), name=f'cbt-gpu-{g}')
for g in gpu_ids]
for p in procs:
p.start()
start_time = time.time()
results = []
finished = 0
while finished < len(gpu_ids):
if not any(p.is_alive() for p in procs):
print('Warning: a worker exited early; reaping remaining tasks...', flush=True)
break
try:
msg = result_queue.get(timeout=5)
except queue_module.Empty:
continue
if msg[0] == 'done':
finished += 1
else:
results.append(msg)
# exit()
# 抽乾剩下排進來的結果
while True:
try:
msg = result_queue.get(timeout=1)
except queue_module.Empty:
break
if msg[0] == 'task':
results.append(msg)
for p in procs:
p.join(timeout=60)
total_time = time.time() - start_time
ok = [r for r in results if r[4]]
fail = [r for r in results if not r[4]]
per_volume = {}
for _, _, vid, level, success, _ in results:
per_volume.setdefault(vid, set()).add(success)
missing = len(tasks) - len(results)
# 一個 volume 算「成功」必須它的(level)全部執行過且全部成功
n_success_volumes = sum(1 for vid in volumes
if per_volume.get(vid, set()) == {True})
print('=' * 60)
print(f'Finished in {total_time / 60:.1f} min | '
f'tasks {len(results)}/{len(tasks)} (ok {len(ok)} / failed {len(fail)} / not-run {missing})')
if missing:
print(f'Warning: {missing} task(s) were never executed (worker crash?)')
print(f'Successful volumes (all levels OK): {n_success_volumes}/{len(volumes)}')
if fail:
print('Failed tasks:')
for _, g, vid, level, _, err in fail:
print(f' [GPU {g}] {vid} {level}: {err}')
if __name__ == '__main__':